How the Misunderstanding that Heroin Addiction Is a Choice and the Stigma Surrounding Medication-Assisted Treatment Leads to More Overdose Deaths

Heroin is an opioid that commonly appears as white or brown powder. Eventually a person can become physically dependent on heroin, meaning the body begins to expect the drug. A sudden withdrawal from the drug can cause intense symptoms such as vomiting, muscle pain, and cravings, often leading to relapse (Shannon, p. 172). Although the initial decision to try heroin may be up to the addict, due to the dependence one develops when using heroin, addiction eventually morphs into an involuntary compulsion. There are many factors out of an individual’s control that influence their likelihood of trying heroin and becoming addicted, such as their genes, the environment they grew up in, and how early they began their drug use (National Institute On Drug Abuse). Much of modern society has a preconceived notion that drug addicts are bad people and that their struggle with addiction could have been avoided if they had made better choices. In short, many people believe that drug addiction is a choice. However, this mentality and the poor image of medication-assisted treatment for addiction the medical community and public commonly hold have been shown to be dangerous and oftentimes lead to more overdose deaths. All in all, despite the fact that the initial decision to try heroin is mostly based on choice, a person does not have control in whether or not they become addicted due to multiple predetermined factors, thus demonstrating that heroin addiction is not a choice and that the stigma surrounding heroin addiction and medicine-assisted treatment, a stigma that has shown to cause more deaths from overdose, is not warranted

Split digraphs

We generalize the class of split graphs to the directed case and show that these split digraphs can be identified from their degree sequences. The first degree sequence characterization is an extension of the concept of splittance to directed graphs, while the second characterization says a digraph is split if and only if its degree sequence satisfies one of the Fulkerson inequalities (which determine when an integer-pair sequence is digraphic) with equality.Comment: 14 pages, 2 figures; Accepted author manuscript (AAM) versio

Orbital Frontal Cortex Projections to Secondary Motor Cortex Mediate Exploitation of Learned Rules.

Animals face the dilemma between exploiting known opportunities and exploring new ones, a decision-making process supported by cortical circuits. While different types of learning may bias exploration, the circumstances and the degree to which bias occurs is unclear. We used an instrumental lever press task in mice to examine whether learned rules generalize to exploratory situations and the cortical circuits involved. We first trained mice to press one lever for food and subsequently assessed how that learning influenced pressing of a second novel lever. Using outcome devaluation procedures we found that novel lever exploration was not dependent on the food value associated with the trained lever. Further, changes in the temporal uncertainty of when a lever press would produce food did not affect exploration. Instead, accrued experience with the instrumental contingency was strongly predictive of test lever pressing with a positive correlation between experience and trained lever exploitation, but not novel lever exploration. Chemogenetic attenuation of orbital frontal cortex (OFC) projection into secondary motor cortex (M2) biased novel lever exploration, suggesting that experience increases OFC-M2 dependent exploitation of learned associations but leaves exploration constant. Our data suggests exploitation and exploration are parallel decision-making systems that do not necessarily compete

Applications of remote sensing in resource management in Nebraska

There are no author-identified significant results in this report

Evaluation of ERTS-1 imagery in mapping and managing soil and range resources in the Sand Hills region of Nebraska

The author has identified the following significant results. Interpretations of imagery from the Earth Resources Technology Satellite (ERTS-1) indicate that soil associations and attendant range sites can be identified on the basis of vegetation and topography using multitemporal imagery. Optical density measurements of imagery from the visible red band of the multispectral scanner(MSS band 5) obtained during the growing season were related to field measurements of vegetative biomass, a factor that closely parallels range condition class on specific range sites. ERTS-1 imagery also permitted inventory and assessment of center-pivot irrigation systems in the Sand Hills region in relation to soil and topographic conditions and energy requirements. Four resource maps of the Upper Loup Natural Resource District located entirely within the Sand Hills region were prepared from ERTS-1 imagery

The use of LANDSAT-1 imagery in mapping and managing soil and range resources in the Sand Hills region of Nebraska

The author has identified the following significant results. Evaluation of ERTS-1 imagery for the Sand Hills region of Nebraska has shown that the data can be used to effectively measure several parameters of inventory needs. (1) Vegetative biomass can be estimated with a high degree of confidence using computer compatable tape data. (2) Soils can be mapped to the subgroup level with high altitude aircraft color infrared photography and to the association level with multitemporal ERTS-1 imagery. (3) Water quality in Sand Hills lakes can be estimated utilizing computer compatable tape data. (4) Center pivot irrigation can be inventoried from satellite data and can be monitored regarding site selection and relative success of establishment from high altitude aircraft color infrared photography. (5) ERTS-1 data is of exceptional value in wide-area inventory of natural resource data in the Sand Hills region of Nebraska

Development offsets for ecosystem services in a rural residential development context: issues for the Murrindindi Shire application

Rural residential development could have a positive or negative effect on the supply of ecosystem services. In most cases, the effect tends to be negative. One way of managing the impact is through a market based instrument. In this paper we present a development offset MBI as a way of cost effectively managing the ecosystem service impact of development in the Murrindindi Shire, Victoria. In this paper we note that design of the instrument is critical to the success of any MBI, including development offsets. Key development offset design issues discussed in this paper include defining what is traded (the metric), facilitating trades in a thin marketplace with high transaction costs, and ensuring the offset is commensurate with the impact.Rural residential development, development offset,, market based instrument, design, Environmental Economics and Policy,

Existence of Equilibrium in Large Double Auctions

We show the existence of a pure strategy, symmetric, increasing equilibrium in double auction markets with correlated private valuations and many participants. The equilibrium we find is arbitrarily close to fully revealing as the market size grows. Our results provide strategic foundations for price-taking behavior in large markets.